New Brain Care Score Tool Helps in Predicting Dementia, Stroke, and Potentially Depression

By: Sam Watanuki | Published: Jul 23, 2024

In December, scientists introduced the Brain Care Score (BCS), a groundbreaking tool for assessing dementia or stroke risk without medical procedures. The BCS evaluates physical, lifestyle, and social-emotional health factors.

This innovative tool now shows promise in predicting the likelihood of depression later in life, according to a recent study.

The Components of the Brain Care Score

The 21-point BCS comprises 12 health-related factors. These include four physical factors: blood pressure, cholesterol, hemoglobin A1c, and body mass index (BMI).

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Additionally, it covers five lifestyle factors like nutrition and exercise, and three social-emotional aspects such as stress management and relationships.

Linking Brain Care Score to Depression

Published in Frontiers in Psychiatry on July 23, the new study highlights that a higher BCS correlates with a lower risk of late-life depression.

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Every five-point increase in BCS reduces the risk of depression by 33% and the combined risk of depression, dementia, and stroke by 27%.

Lifestyle Habits and Brain Health

Dr. Richard Isaacson, a preventive neurologist, emphasized that maintaining healthy lifestyle habits can benefit brain health.

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He noted that staying active, eating well, and minimizing alcohol and smoking can improve both mental and emotional well-being, alongside reducing risks of vascular diseases and dementia.

Significant Findings in Younger Adults

Surprisingly, the study found a strong link between BCS and depression risk among individuals younger than 50.

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This suggests that brain health practices are beneficial across all ages, highlighting the importance of lifelong care for brain health.

Real-World Data from UK Biobank Study

Researchers used health data from over 350,000 people involved in the UK Biobank study.

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Conducted between 2006 and 2010, this study has tracked the health outcomes of over 500,000 individuals aged 40 to 69 in the UK for at least a decade, providing robust data for the BCS study.

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Holistic Approach to Brain Health

Dr. Sanjula Singh, the study’s first author, stressed the importance of a holistic approach to brain health.

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Understanding the interconnected pathways between different brain diseases can help in developing comprehensive strategies to reduce risks of depression, dementia, and stroke.

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Expert Insights on Brain Health

Dr. Jonathan Rosand, cofounder of the McCance Center for Brain Health, explained that the BCS is designed to help anyone improve their brain health.

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He emphasized that increasing your BCS could protect against dementia, stroke, and depression, offering hope for a healthier brain as we age.

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Importance of Seeking Help for Depression

Dr. Isaacson also highlighted the need for older adults experiencing depression to seek help.

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He advised against the “mind over matter” approach and encouraged discussing treatment options with doctors, including therapy and antidepressants.

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Antidepressants and Cognitive Function

Early research suggests that some antidepressants, like escitalopram, may slow the accumulation of beta-amyloid-protein in the brain, a hallmark of Alzheimer’s disease.

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This potential benefit underscores the importance of addressing depression proactively.

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Brain Health Throughout Life

Dr. Isaacson compared brain health to heart health, where early life habits significantly impact later outcomes.

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Just as high cholesterol in your 30s can lead to heart attacks in later years, poor brain health practices can increase risks of neurodegenerative diseases and depression.

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Future Research and Implications

The study’s findings open new avenues for research on brain health.

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Understanding how lifestyle, physical, and social-emotional factors interact to influence brain diseases will be big when it comes to developing effective prevention strategies for dementia, stroke, and depression.

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